A pharmaceutical composition for the treatment of rhinitis by nasal or ocular administration comprises zwitterionic cetirizine, polar lipid liposome, a pharmaceutical acceptable aqueous carrier and, optionally, a pharmaceutically acceptable buffer capable of providing a pH of from pH 4.0 to pH 8.0, with the proviso that, if the polar lipid comprises phospholipid, the amount of phospholipid in the composition from is from 10 mg per mL to 120 mg per mL. Also disclosed are methods for its preparation and methods for treating rhinitis by its nasal or ocular administration.Homogena farmaceutska kompozicija pogodna za liječenje rinitisa nazalnom ili okularnom primjenom koja sadrži cviter ion cetirizina polarni lipidni liposom i farmaceutski prihvatljiv vodeni nosač ukojoj koncentracija cetirizina varira ali ne višeod kada se usporedi sa koncentracijama unutar i izvan struktura liposoma Patent sadrži jošpatentnih zahtjeva
