Peter Raymond Flatt,Christian Holscher,Victor Alan Gault
申请号:
US12677047
公开号:
US09060991B2
申请日:
2008.09.08
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to a peptide analogue of glucagon-like peptide-1 (7-36), which is useful to prophylactically prevent, improve, or reverse the diminished cognitive function associated with these types of disorders, by increasing (or sustaining) the LTP of synaptic transmission. Moreover, sustaining LTP may find utility in the prophylaxis of neurological disease by delaying the onset of impaired cognitive processes, and could serve as a treatment, not only for the diminished cognitive function caused by neurodegeneration, but also for the dysfunctional cognitive processes associated with trauma or age.