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Carbamate benzoxazine propionic acids and acid derivatives for modulation of RORgamma activity and the treatment of disease
专利权人:
发明人:
Thomas D. Aicher,Chad A. VanHuis,John MacLean,Brian M. Andresen,Kenneth J. Barr,Corey Bienstock,Matthew Daniels,Kun Liu,Yuan Liu,Catherine White,Nunzio Sciammetta,Vladimir Simov
申请号:
US15103409
公开号:
US09783511B2
申请日:
2014.12.19
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention provides certain benzoxazine compounds of the Formula (I) or pharmaceutically acceptable salts thereof wherein R1, R2, Ra1, Ra2, Rb1, Rb2, Rc, Rd, and Cy are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds of the Formula (I) or pharmaceutically acceptable salts thereof, and methods of using the compounds of the Formula (I) or pharmaceutically acceptable salts thereof or pharmaceutical compositions comprising the same for treating diseases or conditions mediated by RORgammaT.
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