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CARBOXAMIDE, SULFONAMIDE AND AMINE COMPOUNDS FOR METABOLIC DISORDERS
专利权人:
RIGEL PHARMACEUTICALS; INC.
发明人:
HONG, HUI,XU, XIANG,YU, JIAXIN,SINGH, RAJINDER,DARWISH, IHAB, S,THOTA, SAMBAIAH
申请号:
NZ58529808
公开号:
NZ585298A
申请日:
2008.11.17
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed herein are heterocycloakyl carboxamide, sufonamide and amine derivatives of the given formula, (for example: 5-(1-(4-cyanophenyl)piperidin-4-yloxy)-N-(I-(pyridin-4-ylmethyl)piperidin-4-yl)picolinamide 5-( 1-(4-chlorobenzyl)piperidin-4-yloxy)-N-(1-(pyridin-4-ylmethyl)piperidin-4-yl)benzofuran-2-carboxamide 6-( 1-( 4-cyanobenzyl)piperidin-4-yloxy)-N-(1-(pyridin-4-ylmethyl)piperidin-4-yl) pyridine-3 -sulfonamide) wherein the substituents are as defined within the specification, processes for their preparation, compositions comprising said compounds and uses thereof. Said compounds are useful in treating or preventing metabolic disorders such as type II diabetes, atherosclerosis and cardiovascular disease.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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