AMERICAN UNIVERSITY IN CAIRO;King Abdullah University of Science and Technology
发明人:
El Dorry Hamza,Siam Rania,Mohamed Yasmine M.
申请号：
US201414779293
公开号：
US9963688(B2)
申请日:
2014.03.24
申请国别(地区):
美国
年份:
2018
代理人:
Oblon, McClelland, Maier & Neustadt, L.L.P.
摘要：
EstATII is an esterase that a halotolerant, thermophilic and resistant to a spectrum of heavy metals including toxic concentration of metals. It was isolated from the lowest convective layer of the Atlantis II Red Sea brine pool. The Atlantis II brine pool is an extreme environment that possesses multiple harsh conditions such as; high temperature, salinity, pH and high concentration of metals, including toxic heavy metals. A fosmid metagenomic library using DNA isolated from the lowest convective layer this pool was used to identify EstATII. Polynucleotides encoding EstATII and similar esterases are disclosed and can be used to make EstATII. EstATII or compositions or apparatuses that contain it may be used in various processes employing lipases/esterases especially when these processes are performed under harsh conditions that inactivate other kinds of lipases or esterases.
