A pulsed magnetic particle imaging system includes a magnetic field generating system that includes at least one magnet, the magnetic field generating system providing a spatially structured magnetic field within an observation region of the magnetic particle imaging system such that the spatially structured magnetic field will have a field-free region (FFR) for an object under observation having a magnetic nanoparticle tracer distribution therein. The pulsed magnetic particle imaging system also includes a pulsed excitation system arranged proximate the observation region, the pulsed excitation system includes an electromagnet and a pulse sequence generator electrically connected to the electromagnet to provide an excitation waveform to the electromagnet, wherein the electromagnet when provided with the excitation waveform generates an excitation magnetic field within the observation region to induce an excitation signal therefrom by at least one of shifting a location or condition of the FFR. The pulsed magnetic particle imaging system further includes a detection system arranged proximate the observation region, the detection system being configured to detect the excitation signal to provide a detection signal. The excitation waveform includes a transient portion and a substantially constant portion.L'invention concerne un système d'imagerie à particules magnétiques pulsées comprenant un système de génération de champ magnétique comprenant au moins un aimant, le système de génération de champ magnétique fournissant un champ magnétique structuré spatialement à l'intérieur d'une zone d'observation du système d'imagerie à particules magnétiques de telle sorte que le champ magnétique structuré spatialement possède une zone sans champ (FFR) pour un objet sous observation présentant une distribution de traceur de nanoparticules magnétiques en son sein. Le système d'imagerie à particules magnétiques pulsées comprend également un système d'excitation pulsé disposé à prox
