The method of giving the anti- aging effect to the skin making use of the cosmetics composition and that kind of composition which include non protein characteristic non natural amino acid, is disclosed. This non protein characteristic non natural amino acid is thought that it possesses the accommodation at least for one which relates to skin aging biochemical route especially, LOXL 1 it is the Shin medicine.< Selective figure >It is not非タンパク質性非天然アミノ酸を含む化粧品組成物及びそのような組成物を用いて、皮膚に抗老化効果を与える方法を開示する。この非タンパク質性非天然アミノ酸は、皮膚老化に関わる少なくとも一つの生化学的経路に対する調節作用を有すると考えられ、特に、LOXL-1亢進剤である。【選択図】なし
