A lesion diagnosis apparatus is provided. The lesion diagnosis apparatus using lesion peripheral zone information includes a region division unit configured to divide a region based on lesions or organs included in a medical image, a region exclusion unit configured to exclude regions including lesions or organs other than a diagnostic target lesion among regions divided by the region division unit, and a peripheral region determination unit configured to determine regions other than a diagnostic region among remaining regions other than regions excluded by the region exclusion unit, as peripheral regions for lesion diagnosis.
