PROBLEM TO BE SOLVED: To provide a pharmaceutical preparation which inhibits MK2 and has an excellent effect of preventing and treating rheumatoid arthritis, psoriasis, osteoarthritis, asthma, atherosclerosis, Parkinsons disease, Alzheimers disease, ischemia-reperfusion injury, and periodontitis.SOLUTION: The MK2 inhibitor comprises, as an active ingredient, a compound represented by the specified general formula or its salt, or their solvate.COPYRIGHT: (C)2014,JPO&INPIT【課題】MK2を阻害し、関節リウマチ、乾癬、変形性関節症、喘息、アテローム性動脈硬化症、パーキンソン病、アルツハイマー症、虚血再灌流障害、歯周炎の予防及び治療効果に優れた薬剤の提供。【解決手段】次の一般式で表される化合物、若しくはその塩、又はそれらの溶媒和物を有効成分とするMK2阻害剤。【選択図】なし