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Method for producing chiral 8-(3-amino-piperidin-1-yl)-xanthines and intermediates thereof
专利权人:
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
发明人:
PFRENGLE, WALDEMAR,PACHUR, THORSTEN,NICOLA, THOMAS,DURAN, ADIL
申请号:
NZ58945005
公开号:
NZ589450A
申请日:
2005.11.02
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
The disclosure relates to phthalimido-piperidine derivatives of the general formula (II), wherein the variables are as defined in the specification. The disclosure also provides a process for preparing optically active 3-(phthalimido)piperidine. These compounds are used to further synthesise 8-(3-aminopiperidin-1-yl)xanthine that are suitable for treating diabetes mellitus type I or type II, prediabetes or impaired glucose tolerance, arthritis, obesity, allograft transplantation or osteoporosis caused by calcitonin.
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