Venkata Battula,Michael Andreeff,Sendurai A. Mani,Tapasree Roy Sarkar
申请号:
US14380807
公开号:
US09846160B2
申请日:
2013.02.27
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Methods for determining the presence of cancer stem cells by detecting GD2 expression. Also provided are methods for reducing proliferation of cancer stem cells by contacting the cells with a GD2 targeting agent, such as an anti-GD2 antibody or a GD3 synthase inhibitor. GD3 synthase inhibitor compounds are also provided.