Hemagglutinin-binding peptide

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专利权人:

Tokyo Metropolitan Institute of Medical Science;PeptiDream Inc.

发明人:

Kiichi Kubota,Patrick Reid,Michinori Kohara,Keiichi Masuya,Masaki Ohuchi

申请号：

US16402441

公开号：

US10632187B2

申请日:

2019.05.03

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Disclosed is a hemagglutinin-binding peptide producing an anti-influenza virus effect higher than that of existing peptides. Also disclosed are hemagglutinin-binding peptides comprising a polypeptide having any of the following amino acid sequences (i) to (iv):(i) Thr-MeGly-Asp-MePhe-MePhe-Ser-MeSer-His-Tyr-Thr-Val-Pro-Arg (SEQ ID NO: 1)；(ii) Arg-Val-Ser-MePhe-Thr-Tyr-MePhe-MeSer-Tyr-Thr-Pro-Ser (SEQ ID NO: 2)；(iii) an amino acid sequence with deletions, additions, or substitutions of one or several amino acids in SEQ ID NO: 1 or 2； and(iv) an amino acid sequence having 90% or more sequence identity to that of SEQ ID NO: 1 or 2.

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