A system and method for evaluating a patient status from sampled physiometry for use in respiratory insufficiency management and heart failure assessment is presented. Physiological measures are stored and include direct measures regularly recorded on a substantially continuous basis by a medical device for a patient or measures derived from the direct measures. The physiological measures are sampled, which each relate to a same type of physiometry, and those of the physiological measures, which each relate to a different type of physiometry. A status is determined through analysis of those sampled physiological measures assembled from a plurality of recordation points. The sampled physiological measures are evaluated. Any trends are identified and include one of a status quo and a change, which might affect cardiac performance or respiratory performance. Each such trend is compared to applicable indications of worsening heart failure and respiratory insufficiency to generate a notification of parameter violations.