PROBLEM TO BE SOLVED: To provide peptides derived from tumor-associated antigens capable of binding to human major histocompatibility (MHC) complexes of either class, and capable of eliciting immune response, as well as use methods thereof.SOLUTION: A peptide being a tumor-associated antigen that is able to bind molecules of MHC class I or class II and to elicit immune response. Activated cytotoxic T lymphocyte (CTL) that selectively recognizes the tumor-associated antigen. Use of the peptide for tumor therapy as a vaccine. A method for killing the target cells of a patient by administering an effective number of the CTL to the patient and for expression of a polypeptide comprising the amino acid sequence.SELECTED DRAWING: None【課題】どちらのクラスのヒト主要組織適合性複合体(MHC)にも結合可能であり、かつ免疫応答を引き起こすことができる腫瘍関連抗原に由来するペプチド、及び、その利用方法の提供。【解決手段】MHCクラスI又はIIの分子と結合する能力を有し、かつ免疫応答を引き起こすことができる腫瘍関連抗原であるペプチド。前記腫瘍関連抗原を選択的に認識する活性化細胞傷害性Tリンパ球(CTL)。ペプチドの腫瘍治療、ワクチンとしての使用。前記CTLを患者に効果的な数で投与し、前記アミノ酸配列を含むポリペプチドを任意に発現し患者の標的細胞を殺傷する方法。【選択図】なし