Yang Zheng-Yu,Tran Chinh Viet,Trejo Martin Teresa Alejandra,Link John O.,Zipfel Sheila,Taylor James,Katana Ashley Anne,Kato Darryl,Krygowski Evan S.,Bacon Elizabeth M.,Cottell Jeromy J.
申请号：
NZ72085612
公开号：
NZ720856A
申请日:
2012.11.16
申请国别(地区):
NZ
年份:
2017
代理人:
摘要：
Disclosed are specific velpatasvir analogues as antiviral compounds, optionally in combination with sofosbuvir for the treatment of Hepatitis C Virus. Representative compounds of the present application include methyl { (2S)-1-[(2S)-2-(9-{ 2-[(2S,4S)-1-{ (2R)-2-[(methoxycarbonyl)amino]-2-phenylacetyl} -4-(methoxymethyl)pyrrolidin-2-yl]-1H-imidazol-4-yl} -1,11-dihydro[2]benzopyrano[4’,3’:6,7]naphtho[1,2-d]imidazol-2-yl)-pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl} carbamate.
