Rizzi, Matteo,Ali, Robin,Smith, Alexander,Nishiguchi, Koji
申请号：
AU2016225277
公开号：
AU2016225277A1
申请日:
2016.02.19
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
The invention relates to the use of gene therapy vectors to improve vision by introducing into healthy rod photoreceptor cells of a patient suffering from cone photoreceptor dysfunction and/or degeneration a nucleic acid encoding a gene product that is light-sensitive and/or that modulates endogenous light-sensitive signalling in a photoreceptor cell, such that the range of light intensities to which the rod photoreceptor responds is extended and/or the speed at which the rod photoreceptor responds to light is increased.
