Susedik, Michael E.,Frantz, Karl M.,McKenna, Daniel B.,Huisjen, Martin A.,Adams, Carolyn P.
申请号:
AU2016244200
公开号:
AU2016244200A1
申请日:
2016.10.11
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
#$%^&*AU2016244200A120161103.pdf#####ABSTRACT A system for treating cancer located in a cavity in an organ within a body, the cavity having a tissue surface and a cavity temperature, the system comprising: a solution of iron oxide nanoparticles introduced directly into the cavity, the solution in contact with the tissue surface of the cavity; a chemotherapy agent introduced directly into the cavity; a table for positioning the body containing the cavity; a coreless coil positioned for generating a treatment AC magnetic field that extends through the cavity of the body located on the table; at least two temperature measurement probes for sensing a temperature of the solution in the cavity to generate a sensed solution temperature; a control computer in communication with an Automatic Frequency Control (AFC) circuit, the control computer configured for applying a drive current to the coreless coil to generate the treatment AC magnetic field and for regulating the drive current to the coreless coil to raise the cavity temperature at a predetermined rate and to maintain the cavity at a predetermined temperature for a predetermined time in response to the sensed temperature of the solution in the cavity; wherein the magnetic field has a frequency-between 30kHz and 100kHz; and wherein the cavity is disposed in an organ selected from the group comprising a bladder, a breast, a cervix, a colon, a uterus, a vagina, an esophagus, a stomach and a brain; the cavity either being naturally occurring or created therein.WO 2013/032792 PCT/US2012/051763 3/19 LO~ Q)(