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A BIOSENSOR DEVICE TO DETECT TARGET ANALYTES IN SITU, IN VIVO, AND/OR IN REAL TIME, AND METHODS OF MAKING AND USING THE SAME
专利权人:
发明人:
Anand K. Agarwal,Vijay K. Goel,Dong-Shik Kim,Boren Lin
申请号:
US15764627
公开号:
US20180271423A1
申请日:
2016.10.06
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A biosensor device for the real-time detection of a target analyte includes a receptor component operatively connected to a transducer component which is adapted to interpret and transmit a detectable signal. The receptor component includes a sensing element capable of detecting and binding to at least one target analyte, and a self-assembled monolayer (SAM) layer. The SAM layer is positioned between and in contact with the sensing element and an electrode such that the sensing element, in the presence of the target analyte, causes a detectable signal capable of being transmitted to the electrode. The SAM layer may include an anti-fouling agent. The transducer component includes an electrode (or set of electrodes that includes a working electrode) and microprocessor configured to screen noise and to pick up a detectable signal, such as impedance change at a very low frequency range.
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