Compounds of formula I ** Formula ** in which X indicates CONH2 or CN, Y indicates S, R indicates Ar or Het, R1 indicates phenyl, furyl, thienyl, pyrrolyl, imidazolyl, pyrazolyl, oxazolyl, isoxazolyl, thiazolyl, pyridyl or pyrimidyl, each of which is unsubstituted or mono- or disubstituted by A, OR5 and / or CN, Ar indicates phenyl, which is unsubstituted or is mono-, di- or trisubstituted by A, Hal, (CH2 ) nHet2, (CH2) nOR5, (CH2) nN (R5) 2, (CH2) nCOOR5 and / or (CH2) nCON (R5) 2, Het indicates furyl, thienyl, pyrrolyl, imidazolyl, pyrazolyl, oxazolyl, isoxazolyl, thiazolyl , pyridyl, pyrimidinyl, triazolyl, tetrazolyl, thiadiazole, each of which is not substituted or mono-, di- or trisubstituted by A, (CH2) pHet1, (CH2) pHet2, OH, OA, OAr, Hal and / or (CH2) pCOOR5, Het1 indicates pyridyl, which is unsubstituted or is mono-substituted by A, Het2 indicates pyrrolidinyl, piperidinyl, morpholinyl or piperazinyl, each of which is unsubstituted or monosubstituted p or OH, COOA ', CON (R5) 2, COA and / or A, A' indicates branched or unbranched alkyl having 1-6 C atoms, in 1-7 H atoms they can be replaced by F, A indicates branched or unbranched alkyl having 1-8 C atoms, in which one or two non-adjacent CH2 and / or CH groups may be replaced by N and / or O atoms and / or 1-7 H atoms they can be replaced by F, R5 indicates H or branched or unbranched alkyl having 1-6 C atoms, in which 1-7 H atoms can be replaced by F, Hal indicates F, Cl, Br or I, n indicates 0, 1, 2, 3, 4 or 5, p indicates 0, 1 or 2, and pharmaceutically usable salts, tautomers and stereoisomers thereof, including mixtures thereof in all reasons.Compuestos de fórmula I**Fórmula** en la que X indica CONH2 o CN, Y indica S, R indica Ar o Het, R1 indica fenilo, furilo, tienilo, pirrolilo, imidazolilo, pirazolilo, oxazolilo, isoxazolilo, tiazolilo, piridilo o pirimidilo, cada uno de de los cuales no está sustituido o está mono- o disustituido por A, OR5 y/o CN, Ar indica fenilo, que no está sustituido o es
