JONES, Christopher, Scott,LA GRECA, Susan,LI, Qifang,MUNCHHOF, Michael, John,REITER, Lawrence, Alan
申请号：
MEP34909
公开号：
ME00962B
申请日:
2008.06.16
申请国别(地区):
ME
年份:
2012
代理人:
摘要：
The present invention relates to a compound of the Formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3A, R3B, R4, R5, X, m, and n are as defined herein. Such novel benzamidazole derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.Ovaj izum odnosi se na spoj Formule I (I) ili njegovu farmaceutsk i prihvatljivu so, gdje R1, R2, R3A, R3B, R4, R5, X, m i n su definirani u ovoj specifikaciji . Takvi novi benzimidazolski derivati korisni su u liječenju abnormalnog staničnog rasta, poput raka, kod sisavaca. Ovaj izum također se odnosi na postupak upotrebe takvih spojeva u liječenju abnormalnog staničnog rasta kod sisavaca, osobito ljudi , te na farmaceutske pripravke koji sadrže takve spojeve.
