Use of anti-cgrp antibodies and antibody fragments to prevent or inhibit photophobia or light aversion in subjects in need thereof, especially migraine sufferers
THE UNIVERSITY OF IOWA RESEARCH FOUNDATION;ALDERBIO HOLDINGS LLC
发明人:
KOVACEVICH BRIAN ROBERT,GARCIA-MARTINEZ LEON F.,LATHAM JOHN A.,RUSSO ANDREW F.,KAISER ERIC A.,RECOBER ANA,KUBURAS ADISA,RADDANT ANN C.,SMITH JEFFREY T.L.
申请号：
NZ61863812
公开号：
NZ618638A
申请日:
2012.05.21
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Disclosed is the use of an anti-CGRP antibody or anti-CGRP antibody fragment, anti-CGRP receptor antibody or anti-CGRP receptor antibody fragment, or a polypeptide comprising a fragment of CGRP or a CGRP receptor, in the manufacture of a medicament to treat photophobia or light aversion or preclude the onset of photophobia or photoaversion in a subject, wherein the antibody or antibody fragment or fragment of CGRP or CGRP receptor (CGRP-R) reduces or prevents CGRP-associated photophobia or light aversion.
