Andreas Schoop,Alexander Backes,Joachim Vogt,Lars Neumann,Jan Eickhoff,Stefan Hannus,Kerrin Hansen,Peter Amon,Igor Ivanov,Matthias Borgmann,Chase Smith,Arthur F. Kluge,Krishan Murthi,Rebecca Casaubon
申请号:
US13105957
公开号:
US08232283B2
申请日:
2011.05.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are inhibitors or kinases such as Raf, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer.