Chung-ming Hsieh,Bradford L. McRae,Yuliya Kutskova,John E. Memmott,Michael Roguska,Ian Tomlinson,Carrie Enever,Steven Grant,Mihriban Tuna
申请号:
US13591027
公开号:
US20130171146A1
申请日:
2012.08.21
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention provides an isolated, dual-specific antibody, or an antigen-binding portion thereof, which is specific for human IL-1α and human IL-1β. The dual specific antibodies of the invention also neutralize both human IL-1α and human IL-1β. The invention also provides domain antibodies (dAbs) specific for human IL-1α and human IL-1β.