Robert E. Fischell;Tim A. Fischell;David R. Fischell
发明人:
Robert E. Fischell,David R. Fischell,Tim A. Fischell
申请号:
US13047440
公开号:
US20120065222A1
申请日:
2011.03.14
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed is a cytostatic drug attached to a sterile sheet that is designed to be placed between internal body tissues to prevent the formation of post-operative adhesions, which adhesions are really scar tissue formation. This sheet onto or into which the drug is placed may be either a permanent implant or it may be biodegradable. By impregnating an existing product such as the Johnson & Johnson SURGICEL™ absorbable hemostat gauze-like sheet with an anti-proliferative drug such as sirolimus, the biodegradable, drug impregnated mesh would act as a barrier to cell proliferation and hence be a deterrent to the formation of adhesions or scar tissue. Another embodiment of this invention is a cytostatic drug attached to a sheet that is placed at the site of an anastomosis to decrease scar tissue formation from within the vessel at the site of the anastomosis.