A hand-held system for ultrasound monitoring of internal organs of humans and animals and providing therapy combined with ultrasound is presented. The system comprises a base that functions as a docking station for the smart device. The base comprises ultrasound transducer elements, which are essentially integral with additional electronics, located on its bottom side and a socket into which the smart device can be inserted on its top side. The socket is provided with connecting elements suitable to mechanically and electrically connect the smart device to the base and to allow the base and the smart device to be moved as a single unit.