Embodiments include an interventional guide catheter, comprising: a main tubular shaft with a distal tip and proximal end the main tubular shaft comprising: a main inner structural layer comprising a metallic helically wound multi-filar wire extending from a proximal tube termination to a distal end, a braided wire layer covering the main inner structural layer that extends from the proximal tube termination to the distal end, an outer layer of polymer jacketing fixedly attached to the main inner structural layer and braid layer, an inner layer of polymer jacketing and fixedly attached to the main inner structural layer, a distal tip made of layers of polymer, a distal end curve shape for anatomical conformance that is heat processed in the main metal portion of the structure and a lamination of the inner layer, main inner structural layer, braided wire layer and outer layer. Other embodiments are also included herein.