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Composition of Cinnamomi and Poria, procedure to prepare it and use it
专利权人:
JIANGSU KANION PHARMACEUTICAL CO.; LTD.
发明人:
XIAO, WEI
申请号:
ES01402366
公开号:
ES2377192T3
申请日:
2001.09.13
申请国别(地区):
ES
年份:
2012
代理人:
摘要:
A composition extracted from the stem of Cinnamomum cassia, Poria cocos sclerotia, Paeonia suffruticosa root bark, Paeonia lactiflora root, and Prunus persica or Prunus davidiana seed, in which the composition comprises 1, 3-1, 9 paeoniflorine % and 0.7-1.1% paenonol, and can be obtained through a procedure that includes the steps of: a) obtaining, pruning, washing and cutting the parts of the plants: Cinnamomum cassia stem, Porta cocos sclerocio, bark root Paeonia suffruticosa, root of Paeonia lactiflora, and seed of Prunus persica or Prunus davidiana; b) drying the materials of step (a) to form five medicinal materials: specifically Cinnamomum cassia, Poria cocos, Paeonia suffruticosa, Paeonia lactiflora and Prunus persica or Prunus davidiana, respectively; c) crush Cinnamomum cassia, Prunus persica or Prunus davidiana and Paeonia suffruticosa in thick powders and cut Paeonia lactiflora into slices; d) sterilize the Poria coconuts before granulating 50% of its weight in the fine powder formula and filtering the powder; e) put a complete amount of Paeonia suffruticosa powder through a hot reflux procedure in water and collect its distillate, keeping both the residue and the fluid; f) filter and vacuum dry said distillate to obtain crude Paeonol; g) dissolve the crude paeonol in 95% alcohol to form solution A, and slowly add solution A in a solution of saturated water of β-cyclodextrin while stir at approximately 80 ° C to form a mixture A; h) filter the mixture A and wash the residue with anhydrous alcohol and let the washed residue dry to obtain clathrate A; i) distill a full amount of Cinnamomum cassia in water for four hours and collect its volatile matter, keeping both the residue and the fluid; j) dissolve the volatile matter in 95% alcohol to form a solution B, and slowly add a solution B in a saturated water solution of β-cyclodextrin while stirring at approximately 45 ° C to form a mixture B; k) filter mix B and wash the residue with anhydrous alcohol and l
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