To permeate a medicament efficiently, after relaxing a barrier layer of a skin.SOLUTION: A medicament permeation device 110 comprises: a housing 110； a first electrode 121 and second electrode 122 which are arranged in a mutual proximate state and face outside of the housing 110, and generate an electrical field； a third electrode 133 arranged to face outside of the housing 110, and permeating a medicament in a state of contacting or being close to a skin surface of a prescribed individual； a fourth electrode 134 arranged to face outside of the housing 110, and in which a prescribed voltage is applied between it and the third electrode 133 in a state in which the fourth electrode contacts or is close to other part of the skin surface of the individual； and an insulation cover member 123 for covering the first and second electrodes 121, 122.SELECTED DRAWING: Figure 1【課題】皮膚のバリア層を弛緩させた後、効率的に薬剤を浸透させる。【解決手段】筐体１１０と、筐体１１０の外側に面して相互に近接状態で配置され、電界を発生させる第一電極１２１、および第二電極１２２と、筐体１１０の外側に面して配置され、所定の個体の皮膚表面に接触、または近接状態で薬剤を浸透させる第三電極１３３と、筐体１１０の外側に面して配置され、前記個体の皮膚表面の他部に接触、または近接状態で第三電極１３３との間で所定の電圧が印加される第四電極１３４と、第一電極１２１、および第二電極１２２を覆う絶縁性のカバー部材１２３とを備える薬剤浸透装置１１０。【選択図】図１
