ZHAO, Haoran,KOLLURI, Rao,VALDEZ, Carlos,TSO, Kin,SINGH, Rajinder,RAMPHAL, John
申请号：
ES10732030
公开号：
ES2555982T3
申请日:
2010.01.13
申请国别(地区):
ES
年份:
2016
代理人:
摘要：
A compound having the formula (I): ** Formula ** in which: R1 is selected from hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, -C (O) OR1a, -S (O) R1b and -S ( O) 2R1c； wherein each of R1a, R1b and R1c is, independently, hydrogen, alkyl or phenyl-alkyl； Ra, Rb, Rc and Rd are independently selected from hydrogen and alkyl； m is an integer from one to five； p is an integer from zero to six； R2 is selected from hydroxy, alkyl, alkoxy, cyano, halogen, nitro and trihalomethyl； well: X1, X2 and X3 are CR5； or: one of X1, X2 and X3 is N and the rest are CR5； R5 is selected from hydrogen, halogen and alkyl； R3 and R4, for each occurrence, are independently selected from hydrogen, alkyl, alkoxy, cyano, halogen, hydroxyl and nitro； n is an integer from one to three； Z1, Z2 and Z3 are selected from CR6R6a, N, O and S； Z4 and Z5 are selected from N, C and CR6； R6 is selected from hydrogen, halogen and alkyl； R6a is selected from hydrogen, halogen and alkyl or is absent to satisfy valence requirements； and dashed lines represent a single bond or a double bond； or a salt or a stereoisomer thereof.Un compuesto que tiene la fórmula (I):**Fórmula** en la que: R1 se selecciona entre hidrógeno, alquilo, alquenilo, alquinilo, cicloalquilo, -C(O)OR1a, -S(O)R1b y -S(O)2R1c； en la que cada uno de R1a, R1b y R1c es, de manera independiente, hidrógeno, alquilo o fenil-alquilo； Ra, Rb, Rc y Rd se seleccionan, de manera independiente, entre hidrógeno y alquilo； m es un número entero de uno a cinco； p es un número entero de cero a seis； R2 se selecciona entre hidroxi, alquilo, alcoxi, ciano, halógeno, nitro y trihalometilo； bien: X1, X2 y X3 son CR5； o: uno de X1, X2 y X3 es N y el resto son CR5； R5 se selecciona entre hidrógeno, halógeno y alquilo； R3 y R4, para cada aparición, se seleccionan, de manera independiente, entre hidrógeno, alquilo, alcoxi, ciano, halógeno, hidroxilo y nitro； n es un número entero de uno a tres； Z1, Z2 y Z3 se seleccionan entre CR6R6a, N, O y S； Z4 y Z5 se seleccion
