IMIDAZO BICYCLIC IMMINIUM COMPOUNDS AS ANTITUMOR AGENTS

• 收藏
• 分享

专利权人:

THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

发明人:

CHEN, JAMES,KATO, TOMOYO SAKATA,ONDRUS, ALISON EVELYNN

申请号：

CA2877473

公开号：

CA2877473A1

申请日:

2013.06.19

申请国别(地区):

CA

年份:

2013

代理人:

摘要：

Imidazobicycles having a quaternary nitrogen, i.e. imminium salts, are disclosed. Examples include derivatives of 6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepinium and 2,3-dihydroimidazo[2,1-b]thiazolium salts. The compounds are inhibitors of the Hedgehog pathway and therefore useful as antitumor agents and as probes of the function of Hedgehog-dependent systems.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/