THE GENERAL HOSPITAL CORPORATION D/B/A MASSACHUSETTS GENERAL HOSPITAL; INC.;DANA-FARBER CANCER INSTITUTE;DANA-FARBER CANCER INSTITUTE, INC.
发明人:
FLETCHER, ANNE,TURLEY, SHANNON J.,PAREKKADAN, BIJU,TURLEY, SHANNON, J.
申请号：
CA2867487
公开号：
CA2867487A1
申请日:
2013.03.13
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
A method for suppressing an immune response is provided. The method involves administration of isolated lymphoid tissue-derived suppressive stromal cells (LSSC) to a subject in need of such treatment in an amount effective to suppress the immune response in the subject. The invention also involves a method to isolate LSSC by digesting lymphoid tissue fragments using a combination of an enzyme mix and agitation and then collecting the LSSC. Pharmaceutical preparations comprising LSSC are also provided.
