NASTRI, HORACIO G.,IFFLAND, CHRISTEL,LEGER, OLIVIER,AN, QI,CARTWRIGHT, MARK,MCKENNA, SEAN D.,SOOD, VANITA D.,HAO, GANG
申请号:
CA2856895
公开号:
CA2856895A1
申请日:
2012.11.21
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present application relates to anti-PD-L1 antibodies or antigen binding fragments thereof, nucleic acid encoding the same, therapeutic compositions thereof, and their use to enhance T-cell function to upregulate cell-mediated immune responses and for the treatment of T cell dysfunctional disorders, such as tumor immunity, for the treatment of and cancer.