METHODS OF INHIBITING TUMOR GROWTH BY ANTAGONIZING IL-6 RECEPTOR

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专利权人:

REGENERON PHARMACEUTICALS; INC.

发明人:

ZHANG, LI

申请号：

SG11201401286Q

公开号：

SG11201401286QA

申请日:

2012.11.09

申请国别(地区):

SG

年份:

2014

代理人:

摘要：

The present invention provides methods for inhibiting or attenuating tumor growth in a subject by administering an IL-6 antagonist to the subject. In certain embodiments, the methods of the invention are used to inhibit the growth of an anti-VEGF-resistant tumor in a subject. The IL-6 antagonist may be, e.g., an antibody that specifically binds IL-6R. The IL-6 antagonist may be administered in combination with a VEGF antagonist, and/or an EGFR antagonist.

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