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METHODS OF INHIBITING TUMOR GROWTH BY ANTAGONIZING IL-6 RECEPTOR
专利权人:
REGENERON PHARMACEUTICALS; INC.
发明人:
ZHANG, LI
申请号:
SG11201401286Q
公开号:
SG11201401286QA
申请日:
2012.11.09
申请国别(地区):
SG
年份:
2014
代理人:
摘要:
The present invention provides methods for inhibiting or attenuating tumor growth in a subject by administering an IL-6 antagonist to the subject. In certain embodiments, the methods of the invention are used to inhibit the growth of an anti-VEGF-resistant tumor in a subject. The IL-6 antagonist may be, e.g., an antibody that specifically binds IL-6R. The IL-6 antagonist may be administered in combination with a VEGF antagonist, and/or an EGFR antagonist.
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