Disclosed are a pharmaceutical composition for preventing or treating a cardiovascular disorder comprising amlodipine, rosuvastatin and losartan, and a pharmaceutical complex formulation comprising a first mixture part containing amlodipine and rosuvastatin and a second mixture part containing losartan. The composition and complex formulation comprise rosuvastatin having a particle size (D90) of 50 μm or less, and exhibit excellent dissolution rate, bioavailability, stability and content uniformity, and thus can be useful in pharmaceutical industries.
