Tao Jiang;Yunho Jin;Bei Chen;Tetsuo Uno;Thomas H. Marsilje;Wenshuo Lu;Pierre-Yves Michellys;Wei Pei
发明人:
Pierre-Yves Michellys,Wei Pei,Thomas H. Marsilje,Wenshuo Lu,Bei Chen,Tetsuo Uno,Yunho Jin,Tao Jiang
申请号:
US13172357
公开号:
US08399450B2
申请日:
2011.06.29
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention provides novel pyrimidine and pyridine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine and pyridine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, focal adhesion kinase (FAK), zeta-chain-associated protein kinase 70 (ZAP-70), insulin-like growth factor (IGF-1R), or a combination thereof.