ШТЕРНА БИОЛОГИКАЛС ГМБХ УНД КО. КГ БИОМЕДИЦИНИШЕС ФОРШУНГСЦЕНТРУМ (DE)
发明人:
РУНКЕЛЬ Франк (DE),ШМИДТС Томас (DE)
申请号：
RU2014108515/15
公开号：
RU2014108515A
申请日:
2012.08.02
申请国别(地区):
RU
年份:
2015
代理人:
摘要：
1. Multiple emulsion for applying at least one pharmaceutical or cosmetic active substance which comprises an outer aqueous phase W, O oily phase dispersed in an external aqueous phase and dispersed in the oil phase O internal aqueous phase W, where the internal aqueous phase Wsoderzhitsya at least one electrolyte selected from the group consisting of halides and sulphates of alkali and alkaline earth metals, and at least one hydrophilic active substance, wherein the multiple emulsion is characterized in that: - the external aqueous phase Wsoderzhit hydrophilic emulsifier, which is a a polymer of ethylene oxide and propylene oxide, the oil phase O u triacylglycerides formed, and a lipophilic emulsifier is selected from the group dimetikonov.2. Multiple emulsion according to Claim. 1, characterized in that the hydrophilic emulsifier is poloksamer.3. Multiple emulsion according to any one of claims. 1 or 2, characterized in that the lipophilic emulsifier is a linear polyester with dimethicone and alkyl gruppami.4. Multiple emulsion according to Claim. 1, characterized in that the triacylglycerides are esters of saturated fatty kislot.5. Multiple emulsion according to Claim. 1, characterized in that the electrolyte is NaCl, NaCl and the mixture MgSOili MgSO.6. Multiple emulsion according to Claim. 1, characterized in that the hydrophilic surfactant is MgSO.7. Multiple emulsion according to claim 1, characterized in that the hydrophilic surfactant is an oligonucleotide, preferably with the oligonucleotide sequence according SEQIDNo: 1 - SEQIDNo:. 148 or SEQIDNo: 150.8. Multiple Emulsion n1. Множественная эмульсия для нанесения, по меньшей мере, одного фармацевтического или косметического активного вещества, которая включает внешнюю водную фазу W1, масляную фазу О, диспергированную во внешней водной фазе, и диспергированную в масляной фазе О внутреннюю водную фазу W2, где во внутренней водной фазе W2 содержится, по меньшей мере, один электролит, выбранный из группы галог
