USE OF ANTIBIOTICS WITH SPECIFIC THERAPEUTIC ACTIVITIES COMBINED WITH THE SIMULTANEOUS USE OF LACTOBACILLI AND/OR BIFIDOBACTERIA WITH A NON-TRANSFERABLE ANTIBIOTIC RESISTANCE, HAVING THE SAME THERAPEUTIC INDICATION
The present invention relates to the use of antibiotics with specific therapeutic activities combined with the simultaneous use of lactobacilli and/or bifidobacteria having a non-transferable antibiotic resistance and with the same therapeutic indication as said antibiotics. In particular, the present invention relates to a composition comprising or, alternatively, consisting of antibiotics suitable for the treatment of acute and chronic intestinal infections due to gram-positive and gram-negative bacteria； diarrheic syndromes； diarrhea due to an imbalance of the intestinal microflora such as for example, summer diarrhea, traveler's diarrhea and enterocolitis； pre- and postoperative prophylaxis of infectious complications in gastrointestinal surgery； gastrointestinal diseases such as irritable bowel syndrome (IBS), constipation, alterations of intestinal microflora； chronic inflammatory intestinal diseases (IBD) and inflammations due to Helicobacter pylori； said antibiotics belonging to the rifamycin family, preferably rifaximin, being combined with specific strains of bacteria belonging to the species Bifidobacterium longum having the same therapeutic indication as said antibiotics.
