The invention refers to a natural herbicide with active ingredients naturally produced essential oils, either plain or in mixtures. Also, it refers to its production method which uses nanotechnology techniques and advanced encapsulation techniques by lyophilization as well as to the use of the finished product.The composition of this natural herbicide is characterized by the basic component, which is either a plain naturally produced essential oil, or suitable combination of naturally produced essential oils, in combination with an encapsulation carrier, which by employing a suitable solvent are mixed, homogenized and lyophilized to result in the production of a wettable powder.The produced wettable powder is dispersible in water and can be used for the weed control in various crops.The key feature of the invention is the applicability of this natural herbicide in organic farming as well as in integrated agricultural production systems.