Compounds 4 - {7 - methyl - 3 - oxo - 8 - [3 - (trifluoromeil cyclohexa-2,5-dien-1-ylidene) - 2.4 - dien - triazin-1-yl] 2,3,5,8 - tetrahydro - [1,2,4] triazolo [4,3-a] pyrimidin-5-yl) benzonitrile； Pharmaceutical composition； a method for treating a disease or a condition in which participating hne, such as COPD, pneumonia, Asthma, rhinitis, and Among others.

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专利权人:

CHIESI FARMACEUTICI S.P.A.

发明人:

ALCARAZ, LILIAN,HEALD, ROBERT ANDREW,SUTTON, JONATHAN MARK,ARMANI, ELISABETTA,CAPALDI, CARMELIDA

申请号：

CL2015001678

公开号：

CL2015001678A1

申请日:

2015.06.16

申请国别(地区):

CL

年份:

2015

代理人:

摘要：

Pyrimidinone compounds defined herein exhibit human neutrophil elastase inhibitory properties and are useful for treating diseases and conditions in which HINE is implicated.<；p>；COMPUESTOS DERIVADOS DE 4-{7-METIL-3-OXO-8-[3-(TRIFLUOROMETIL)-CICLOHEXA-2,4-DIEN-1-IL]-2,3,5,8-TETRAHIDRO-[1,2,4]-TRIAZOLO-[4,3-A]-PIRIMIDIN-5-IL}-BENZONITRILO SUSTITUIDOS； COMPOSICIÓ；N FARMACÉ；UTICA； Ú；TILES PARA EL TRATAMIENTO DE ENFERMEDAD ASOCIADA A HNE, TAL COMO EPOC, NEUMONÍ；A, ASMA, RINITIS, ENTRE OTRAS.<；/p>；

来源网站：

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