UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION; INC.
发明人:
DANIELL, HENRY
申请号:
EP09814927
公开号:
EP2303296A4
申请日:
2009.05.27
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
Disclosed herein is the successful expression of the plague F1-V fusion antigen in chloroplasts. Parenteral and/or oral administration of chloroplast produced antigens effectively elicit protective immune responses in vivo. Disclosed herein is the first report of a plant-derived oral vaccine that protected animals from live Y. pestis challenge, bringing the likelihood of lower-cost vaccines closer to reality.