Sun Pharmaceutical Industries Australia Pty Limited
发明人:
Winzer, Thilo,Graham, Ian
申请号：
AU20180203033
公开号：
AU2018203033(A1)
申请日:
2018.05.01
申请国别(地区):
澳大利亚
年份:
2018
代理人:
摘要：
Abstract The disclosure relates to a plant of the genus Papaver that comprises one or more genomic modifications in multiple genes encoding codeine 3-0-demethylase (CODM) and which do 5 not express detectable codeine 3-0-demethylase activity wherein said modified plant is further modified in one or more thebaine 6-0-demethylase genes (T6ODM) to reduce or abrogate thebaine 6-0-demethylase activity said plant is characterised by increased thebaine content when compared to an unmodified plant of the same species.
