Mohammed Benghezal;Aleksandra Weronika Debowski;Miriam Sehnal;Yakhya Dieye;Se-Hoon Park;Barry Marshall
发明人:
Mohammed Benghezal,Aleksandra Weronika Debowski,Miriam Sehnal,Yakhya Dieye,Se-Hoon Park,Barry Marshall
申请号：
US14003786
公开号：
US09115363B2
申请日:
2012.03.09
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to a gene expression and eradication system for Helicobacter pylori (H. pylori). In particular, the present invention relates to a genetic construct comprising, in the 5′-3′ direction: (a) a promoter sequence and (b) a DNA sequence of interest, wherein the promoter sequence comprises a polynucleotide sequence capable of regulating expression of the DNA sequence of interest in Helicobacter pylori and wherein said promoter sequence is modified to comprise a tetracycline (tet) operator sequence.
