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HEPATITIS C VIRUS INHIBITORS
专利权人:
BRISTOL-MYERS SQUIBB COMPANY
发明人:
LOPEZ, OMAR D
申请号:
NZ59498110
公开号:
NZ594981A
申请日:
2010.03.29
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
594981 Disclosed are compounds of Formula (I) as defined in the specification and compositions comprising such compounds. These compounds are useful antiviral agents, especially in inhibiting the function of the NS5A protein encoded by Hepatitis C virus (HCV). Thus, the disclosure also concerns a method of treating HCV related diseases or conditions by use of these compounds or a composition comprising such compounds. Specific embodiments of the compounds include: methyl ((1S)-1-(((2S)-2-(4-(4'-(2-((2S)-1-((2S)-2-((methoxycarbonyl)arnino)-3-methylbutanoyl)-2-pyrrolidinyl)-1H-imidazo-1-4-yl)-1,1'-bi(3-cyclohexen-lyl)-4-yl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate, and methyl ((1R)-2-((2S)-2-(4-(4-(4-(2-((2S)-1-((2R)-2-((methoxycarbonyl)amino)-2-phenylacetyl)-2-pyrrolidinyl)-1H-imidazol-4-yl)bicyclo[2.2.2]oct-1-yl)phenyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)-2-oxo-1-phenylethyl)carbamate;
来源网站:
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