An arm restraint system is provided for restraining movement of an arm of a patient's body lying over a top surface of a table. A padded restraint is configured to at least partially receive the arm of said patient to thereby maintain the arm at a position laterally adjacent to the patient's body without the arm being restrained by tucking. In one example, the system includes a rigid support frame located at a lateral edge of said table and the padded restraint is securely fixed to the rigid support frame via a repositionable fastener to inhibit movement of the patient's arm relative to the rigid support frame.