AGENT ANTICANCÉREUX, PROCÉDÉ D'INDUCTION DE L'APOPTOSE DE CELLULES CANCÉREUSES ET PROCÉDÉ DE CRIBLAGE D'UN AGENT ANTICANCÉREUX

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专利权人:

Medical Care Proteomics Biotechnology Co.; Ltd.

发明人:

申请号：

EP10799859.3

公开号：

EP2455103A1

申请日:

2010.07.14

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

Disclosed is an anti-cancer agent which can inhibit the progression of cell cycle in the M phase, unlike taxane anti-cancer agents. The anti-cancer agent comprises a compound capable of inhibiting specifically the expression and/or functions of RBM8A depicted in SEQ ID NO: 1, Magoh depicted in SEQ ID NO: 3 or an isoform thereof. The anti-cancer agent can inhibit the expression and/or functions of RBM8A or Magoh in cancer cells to terminate the cell cycle in the M phase, thereby inhibiting the proliferation of the cells. Therefore, the anti-cancer agent can inhibit the proliferation of cancer cells and induce the apoptosis of cancer cells, leading to the cure of cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/