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Benzodiazepine bromodomain inhibitor
专利权人:
GLAXOSMITHKLINE LLC
发明人:
GOSMINI ROMAIN LUC MARIE,MIRGUET OLIVIER
申请号:
NZ59925810
公开号:
NZ599258A
申请日:
2010.08.06
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
The disclosure relates to a compound 2-[(4S)-6-(4-Chlorophenyl)-1-methyl-8-(methyloxy)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide which is represented by structural formula (I) and a pharmaceutically acceptable salt thereof; which is suitable for use in the treatment of a chronic autoimmune and inflammatory condition and also for treating cancer selected from hematological including leukaemia, epithelial including lung, breast and colon carcinomas, midline carcinomas, mesenchymal, hepatic, renal and neurological tumours.
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