The present Invention relates to Antibodies that bind to the Protein that contains three human t-cell Immunoglobulin and Mucin domain (tim-3)And may be useful for treating Solid tumors and hematological alone and in combination with chemotherapy and Ionizing Radiation.Claim 1: an Antibody that binds to Human tim-3 (SEQ ID no. 1), the Antibody that includes hcdr1, hcdr2, hcdr3, lcdr1, lcdr2 and lcdr3,Where: (a) hcdr1 has the amino acid sequence of SEQ ID no. 2, hcdr2 has the amino acid sequence of SEQ ID no. 3, hcdr3 has the amino acid sequence of SEQ ID no. 4Lcdr1 has the amino acid sequence of SEQ ID no. 5, lcdr2 has the amino acid sequence of SEQ ID no. 6And lcdr3 has the amino acid sequence of SEQ ID no. 7 (b) hcdr1 has the amino acid sequence of SEQ ID no. 14, hcdr2 has the amino acid sequence of SEQ ID no. 15Hcdr3 has the amino acid sequence of SEQ ID no. 16, lcdr1 has the amino acid sequence of SEQ ID no. 17, lcdr2 has the amino acid sequence of SEQ ID no. 18And lcdr3 has the amino acid sequence of SEQ ID no. 19 or (c) hcdr1 has the amino acid sequence of SEQ ID no. 26, hcdr2 has the amino acid sequence of SEQ ID no. 27Hcdr3 has the amino acid sequence of SEQ ID no. 28, lcdr1 has the amino acid sequence of SEQ ID no. 29, lcdr2 has the amino acid sequence of SEQ ID no. 30And lcdr3 has the amino acid sequence of SEQ ID no. 31.La presente solicitud se refiere a anticuerpos que se unen a la proteína 3 que contiene inmunoglobulina de célula T humana y dominio de mucina (Tim-3), y pueden ser útiles para tratar tumores sólidos y hematológicos solos y en combinación con quimioterapia y radiación ionizante. Reivindicación 1: Un anticuerpo que se une a Tim-3 humana (SEQ ID Nº 1), el anticuerpo que comprende, HCDR1, HCDR2, HCDR3, LCDR1, LCDR2 y LCDR3, en donde: a) HCDR1 tiene la secuencia de aminoácidos de SEQ ID Nº 2, HCDR2 tiene la secuencia de aminoácidos de SEQ ID Nº 3, HCDR3 tiene la secuencia de aminoácidos de SEQ ID Nº 4, LCDR1 tiene la secuencia de aminoácidos de
