A surgical drape includes a first sheet of surgical drape material secured to a second sheet of surgical drape material by a removable adhesive disposed along an overlapping joint. A pre-defined work-through area is defined in a central portion of the surgical drape, and the overlapping joint intersects with the work-through. Optionally, removable areas of pre-defined size and shape around the work-through area are defined by frangible paths so that the work-through area can be selectively enlarged by tearing along one or more of the frangible paths to remove one or more of the removable areas. A tab facilitates gripping by a user for separating the first sheet from the second sheet. The work-through area may be a pre-cut opening or a pre-defined tear-away removable portion of the first and/or second sheets.