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PEPTIDE-BASED STAT INHIBITOR
专利权人:
发明人:
Nadya I. Tarasova,Olga Timofeeva,Vadim Gaponenko,Alan O. Perantoni,Sergey G. Tarasov,Christopher J. Michejda
申请号:
US15397053
公开号:
US20170204148A1
申请日:
2017.01.03
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A peptide or peptidomimetic comprising the amino acid sequence of the second helix of a STAT protein, or a variant of such sequence, wherein the peptide or peptidomimetic comprises about 40 or fewer amino acids and binds to a STAT protein, as well as a method of inhibiting a STAT protein in a cell, a method of treating or preventing a disease associated with STAT overexpression in a host, and related compounds, compositions, and methods.
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