PETKOVICH Martin P;PEERS Susan H;MELNICK Joel Z;TABASH Samir P;OPKO Ireland Global Holdings Ltd;WHITE Jay A;BISHOP Charles W;STRUGNELL Stephen A
发明人:
MELNICK Joel Z,WHITE Jay A,PETKOVICH Martin P,TABASH Samir P,BISHOP Charles W,PEERS Susan H,STRUGNELL Stephen A
申请号:
IL25825918
公开号:
IL258259D0
申请日:
2018.03.20
申请国别(地区):
IL
年份:
2018
代理人:
摘要:
Methods, compositions, and kits for adjunctive therapy using 25-hydroxyvitamin D are disclosed. The 25-hydroxyvitamin D may be administered with an agent that increases the risk of hypocalcemia, such as cinacalcet or a salt thereof, and/or an anticancer agent. The adjunctive therapy is effective to treat and prevent iatrogenic hypocalcemia and/or secondary hyperparathyroidism, as well as delay cancer progression and the time to a post-treatment skeletal related event.